Withdrawal Interval (WDI) Recommendations
for sheep, taken from the FARAD Digests
WARNING!
Extra Label Use of this drug is permissible under AMDUCA only if such use is by or on the lawful written or oral order of a licensed veterinarian within the context of a valid veterinarian-client-patient relationship.
Below are the WDI recommendations for the various route and dosage combination(s) for extra-label administration of in sheep.
| Drug | Route
Abbreviations
(EPI) Epidural(INF) Infiltration(IM) Intramuscular
(IV) Intravenous(PO) Oral
(SC) Subcutaneous(TOP) Topical
|
Dosage | Frequency | Meat WDI | Milk WDI |
|---|---|---|---|---|---|
| acepromazine | IM | up to 0.44 mg/kg | single and multiple doses | 7 days | 48 hours |
| acepromazine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| acepromazine | Reference(s): Drugs approved for small ruminants | ||||
| acepromazine | |||||
| acepromazine | IV | up to 0.13 mg/kg | single and multiple doses | 7 days | 48 hours |
| acepromazine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| acepromazine | Reference(s): Drugs approved for small ruminants | ||||
| activated charcoal | PO | n.a. | n.a. | 0 days | 0 days |
| activated charcoal | Reference(s): Antidotes in food animal practice | ||||
| atropine | IV | up to 0.2 mg/kg | every 4-6 hours | 28 days | 6 days |
| atropine | Warnings:treatment of organophosphate toxicosis; be sure there are no organophosphates residues |
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| atropine | Reference(s): Antidotes in food animal practice | ||||
| atropine | |||||
| atropine | IM | up to 0.2 mg/kg | every 4-6 hours | 28 days | 6 days |
| atropine | Warnings:treatment of organophosphate toxicosis; be sure there are no organophosphates residues |
||||
| atropine | Reference(s): Antidotes in food animal practice | ||||
| atropine | |||||
| atropine | SC | up to 0.2 mg/kg | every 4-6 hours | 28 days | 6 days |
| atropine | Warnings:treatment of organophosphate toxicosis; be sure there are no organophosphates residues |
||||
| atropine | Reference(s): Antidotes in food animal practice | ||||
| detomidine | IV | up to 0.08 mg/kg | single and multiple doses | 3 days | 72 hours |
| detomidine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| detomidine | |||||
| detomidine | IM | up to 0.08 mg/kg | single and multiple doses | 3 days | 72 hours |
| detomidine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| dimethyl sulfoxide (DMSO) | TOP | n.a. | n.a. | 4 days | 96 hours |
| dimethyl sulfoxide (DMSO) | Warnings:pharmaceutical grade DMSO only |
||||
| dimethyl sulfoxide (DMSO) | Reference(s): Residue avoidance after topical application of veterinary drugs and parasiticides | ||||
| epinephrine | IV | n.a. | multiple doses | 0 days | 0 days |
| epinephrine | Warnings:endogenous substance with rapid metabolism |
||||
| epinephrine | Reference(s): Antidotes in food animal practice | ||||
| epinephrine | |||||
| epinephrine | IM | n.a. | multiple doses | 0 days | 0 days |
| epinephrine | Warnings:endogenous substance with rapid metabolism |
||||
| epinephrine | Reference(s): Antidotes in food animal practice | ||||
| epinephrine | |||||
| epinephrine | SC | n.a. | multiple doses | 0 days | 0 days |
| epinephrine | Warnings:endogenous substance with rapid metabolism |
||||
| epinephrine | Reference(s): Antidotes in food animal practice | ||||
| fenbendazole | PO | 5 mg/kg | single dose | 28 days | |
| fenbendazole | Reference(s): Extralabel drug use in small ruminants | ||||
| florfenicol | SC | 40 mg/kg | single dose | 42 days | |
| florfenicol | Warnings:Meat and Milk WDI are based on limited data and vets are still encouraged to contact FARAD for WDI each time they use ELDU in case new data is available. |
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| florfenicol | Reference(s): Extralabel drug use in small ruminants | ||||
| florfenicol | |||||
| florfenicol | IM | 20 mg/kg | every 48 hours x 2 | 60 days | 168 hours plus test1 |
| florfenicol | Warnings:Meat and Milk WDI are based on limited data and vets are still encouraged to contact FARAD for WDI each time they use ELDU in case new data is available. |
||||
| florfenicol | Reference(s): Extralabel drug use in small ruminants | ||||
| florfenicol | 1 Important! FARAD recommends testing the milk from treated animals to ensure it is free of residues of the parent drug and drug metabolites before it is marketed for human consumption. |
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| flunixin meglumine | IM | 2.2 mg/kg | single dose | 15 days | 96 hours |
| flunixin meglumine | Warnings:Meat and Milk WDI are based on limited data and vets are still encouraged to contact FARAD for WDI each time they use ELDU in case new data is available. |
||||
| flunixin meglumine | Reference(s): Extralabel drug use in small ruminants | ||||
| flunixin meglumine | |||||
| flunixin meglumine | IV | 2.2 mg/kg | single dose | 10 days | 72 hours |
| flunixin meglumine | Warnings:Meat and Milk WDI are based on limited data and vets are still encouraged to contact FARAD for WDI each time they use ELDU in case new data is available. |
||||
| flunixin meglumine | Reference(s): Extralabel drug use in small ruminants | ||||
| guaifenesin | IV | up to 100 mg/kg | single and multiple doses | 3 days | 48 hours |
| guaifenesin | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| ketamine | IM | up to 10 mg/kg | single and multiple doses | 3 days | 48 hours |
| ketamine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| ketamine | |||||
| ketamine | IV | up to 2 mg/kg | single and multiple doses | 3 days | 48 hours |
| ketamine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| ketamine | Reference(s): Drugs approved for small ruminants | ||||
| lidocaine w/epinephrine | INF | n.a. | single and multiple doses | 1 day | 24 hours |
| lidocaine w/epinephrine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| lidocaine w/epinephrine | |||||
| lidocaine w/epinephrine | EPI | n.a. | single and multiple doses | 1 day | 24 hours |
| lidocaine w/epinephrine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| meloxicam | PO | 1 mg/kg | single dose | 15 days | |
| meloxicam | Warnings:Meat and Milk WDI are based on limited data and vets are still encouraged to contact FARAD for WDI each time they use ELDU in case new data is available. |
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| meloxicam | Reference(s): Extralabel drug use in small ruminants | ||||
| oxytetracycline (long-acting) | SC | 20 mg/kg | single dose | 35 days | 144 hours plus test1 |
| oxytetracycline (long-acting) | Warnings:Meat and Milk WDI are based on limited data and vets are still encouraged to contact FARAD for WDI each time they use ELDU in case new data is available. |
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| oxytetracycline (long-acting) | Reference(s): Extralabel drug use in small ruminants | ||||
| oxytetracycline (long-acting) | 1 Important! FARAD recommends testing the milk from treated animals to ensure it is free of residues of the parent drug and drug metabolites before it is marketed for human consumption. |
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| pralidoxime (2-PAM) | IM | up to 30 mg/kg | every 8 hours | 28 days | 6 days |
| pralidoxime (2-PAM) | Warnings:treatment of organophosphate toxicosis; be sure there are no organophosphates residues |
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| pralidoxime (2-PAM) | Reference(s): Antidotes in food animal practice | ||||
| tetracyclines | Top (Topical) | n.a. | n.a. | 0 days | 0 days |
| tetracyclines | Warnings:provided there is no oral ingestion |
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| tetracyclines | Reference(s): Residue avoidance after topical application of veterinary drugs and parasiticides | ||||
| thiopental | IV | up to 5 mg/kg | n.a. | 1 day | 24 hours |
| thiopental | Reference(s): Drugs approved for small ruminants | ||||
| vitamin K1 (phytonadione) | IV | 0.5 - 2.5 mg/kg | per label | 0 days | 0 days |
| vitamin K1 (phytonadione) | Reference(s): Antidotes in food animal practice | ||||
| vitamin K1 (phytonadione) | |||||
| vitamin K1 (phytonadione) | IM | 0.5 - 2.5 mg/kg | per label | 0 days | 0 days |
| vitamin K1 (phytonadione) | Reference(s): Antidotes in food animal practice | ||||
| vitamin K1 (phytonadione) | |||||
| vitamin K1 (phytonadione) | SC | 0.5 - 2.5 mg/kg | per label | 0 days | 0 days |
| vitamin K1 (phytonadione) | Reference(s): Antidotes in food animal practice | ||||
| xylazine | IM | 0.05 - 0.3 mg/kg | single and multiple doses | 4 days | 24 hours |
| xylazine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| xylazine | |||||
| xylazine | IM | 0.3 - 2.0 mg/kg | single and multiple doses | 10 days | 120 hours |
| xylazine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| xylazine | |||||
| xylazine | IV | 0.016 - 0.1 mg/kg | single and multiple doses | 5 days | 72 hours |
| xylazine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
| xylazine | Reference(s): Drugs approved for small ruminants | ||||
| yohimbine | IV | up to 0.3 mg/kg | single and multiple doses | 7 days | 72 hours |
| yohimbine | Reference(s): Extralabel use of tranquilizers and general anesthetics | ||||
If you have further questions or concerns, please contact our ELDU advice team.
